Shared Resources

Below is a listing of facilities and expertise available to all Neuroscience investigators. If you would like to add a shared resource, please contact the Office of Neuroscience Research.

To search for a shared resource, enter a keyword or phrase.

**Shared Services, Equipment, and Expertise**
Facility	Services offered	Contact
Alafi Neuroimaging	Confocal and multiphoton microscopy; digital whole-slide scanning	Kris Hyrc
AMP (Anatomic and Molecular Pathology) Lab	Immunohistochemistry, histology, molecular pathology, tissue microarrays, digital imaging
Animal Behavior	Phenotyping of small animal behavior including assessment of motor/sensorimotor functions (e.g., rotarod, gait analysis), learning and memory capabilities (e.g., Morris water maze), altered emotionality, social behaviors, and visual thresholds	David Wozniak
Animal Models	Models for stroke, traumatic brain injury	Ernie Gonzales
Bakewell Neuroimaging	Confocal and multiphoton microscopes for live or fixed tissue imaging; low light imaging system; FRET/FRAP; upright or inverted microscope capability; post acquisition work station (Metamorph, Image J, Adobe Photoshop)	Dennis Oakley, Paul Taghert
Biology Imaging	Confocal and deconvolution microscopy	Olga Pontes
Biology - Low Light Imaging	Low Light Imaging for bioluminescence	Luciano Marpegan
Biomedical Informatics	Web tools, sequence analysis, biospecimen inventory management, clinical study data management (consultation), microarray analyses (expression, aCGH, SNP, ChIP-CHIP, and ChIP-Seq)	help@bmi.wustl.edu
Biostatistics Consulting	Design of experiments and clinical trials, protocol development, database management, assistance with grant preparation, statistical analysis of data	Ken Schechtman
Central Neuroimaging Data Archive (CNDA)	Storage and analysis of MRI, PET, and CT imaging data	Dan Marcus
Histology and Microscopy	Full service histology, Zeiss Apotome structured resolution microscope, stereoscope, brightfield/fluorescence microscopes, transmission EM, scanning EM	Howard Wynder
In Vitro Physiology	In vitro brain slice preparations, whole-cell recording (cultured neurons or transfected cells), data analysis	Steve Mennerick
In Vivo Physiology	EEG, EMG, evoked synaptic responses from dentate granule cell layer, assessment of tetanus-induce long-term synaptic potentiation	Kel Yamada
Mouse Genetics	Production and maintenance of transgenic or chimeric mice, pcr genotyping, speed congenics, reproductive services including cryopreservation, in vitro fertilization, rederivations	Mia Wallace
Multiple Sclerosis Research Interest Group	Multiple Sclerosis animal models - EAE	Anne Cross
Pain	Behavioral tests of baseline pain sensitivity (mechanical,heat, cold, chemical, visceral); models of persistent pain (inflammatory and neuropathic); studies of analgesia in response to systemically- or intrathecally-administered drugs	Rob Gereau
Protein and Nucleic Acid Chemistry Laboratories (PNACL)	Automated DNA sequencing, synthetic oligonucleotides, Edman degradation protein sequencing	Erin Ramshur, Misty Veschak, Greg Grant
Proteomics		Reid Townsend
RNAi	Viral vector-based RNAi technology to alter gene function in primary cultures	rnairequest@watson.wustl.edu
Sensory Function	Standard noninvasive functional assays of inner ear/auditory brainstem function, and retina/central visual pathways	Kevin Ohlemiller
Transgenic Vectors	Design, construction of mouse transgenes and gene targeting vectors using recombineering technology; mouse ES cell screening (pcr and southern blot)	Renate Lewis
Viral Vectors	Assist in design/preparation of lentiviral vectors and adeno-associated viral vectors; some shared molecular biology equipment available	Mingjie Li, Joy Snider