Below is a listing of facilities, services, and expertise are available to all Neuroscience investigators. If you would like to add a facility or expertise, please contact the Office of Neuroscience Research.
| Facility | Services offered | Contact |
Alafi Neuroimaging | Confocal and multiphoton microscopy; digital whole-slide scanning | Kris Hyrc |
AMP (Anatomic and Molecular Pathology) Lab | Immunohistochemistry, histology, molecular pathology, tissue microarrays, digital imaging | |
AMP (Anatomic and Molecular Pathology) Lab | Immunohistochemistry, histology, molecular pathology, tissue microarrays, digital imaging | |
Animal Behavior | Phenotyping of small animal behavior including assessment of motor/sensorimotor functions (e.g., rotarod, gait analysis), learning and memory capabilities (e.g., Morris water maze), altered emotionality, social behaviors, and visual thresholds | David Wozniak |
Animal Models | Models for stroke, traumatic brain injury | Ernie Gonzales |
Bakewell Neuroimaging | Confocal and multiphoton microscopes for live or fixed tissue imaging; low light imaging system; FRET/FRAP; upright or inverted microscope capability; post acquisition work station (Metamorph, Image J, Adobe Photoshop) | Dennis Oakley, Paul Taghert |
Biology - Low Light Imaging | Low Light Imaging for bioluminescence | Luciano Marpegan |
Biology Imaging | Confocal and deconvolution microscopy | Olga Pontes |
Biomedical Informatics | Web tools, sequence analysis, biospecimen inventory management, clinical study data management (consultation), microarray analyses (expression, aCGH, SNP, ChIP-CHIP, and ChIP-Seq) | help@bmi.wustl.edu |
Biostatistics Consulting | Design of experiments and clinical trials, protocol development, database management, assistance with grant preparation, statistical analysis of data | Ken Schechtman |
Central Neuroimaging Data Archive (CNDA) | Storage and analysis of MRI, PET, and CT imaging data | Dan Marcus |
Histology and Microscopy | Full service histology, Zeiss Apotome structured resolution microscope, stereoscope, brightfield/fluorescence microscopes, transmission EM, scanning EM | Howard Wynder |
In Vitro Physiology | In vitro brain slice preparations, whole-cell recording (cultured neurons or transfected cells), data analysis | Steve Mennerick |
In Vivo Physiology | EEG, EMG, evoked synaptic responses from dentate granule cell layer, assessment of tetanus-induce long-term synaptic potentiation | Kel Yamada |
Mouse Genetics | Production and maintenance of transgenic or chimeric mice, pcr genotyping, speed congenics, reproductive services including cryopreservation, in vitro fertilization, rederivations | Mia Wallace |
Multiple Sclerosis Research Interest Group | Multiple Sclerosis animal models - EAE | Anne Cross |
Pain | Behavioral tests of baseline pain sensitivity (mechanical,heat, cold, chemical, visceral); models of persistent pain (inflammatory and neuropathic); studies of analgesia in response to systemically- or intrathecally-administered drugs | Rob Gereau |
PNACL | | |
Protein and Nucleic Acid Chemistry Laboratories (PNACL) | Automated DNA sequencing, synthetic oligonucleotides, Edman degradation protein sequencing | Erin Ramshur, Misty Veschak, Greg Grant |
Proteomics | | Reid Townsend |
RNAi | Viral vector-based RNAi technology to alter gene function in primary cultures | rnairequest@watson.wustl.edu |
Sensory Function | Standard noninvasive functional assays of inner ear/auditory brainstem function, and retina/central visual pathways | Kevin Ohlemiller |
Sensory/RCAVS | | |
Transgenic Vectors | Design, construction of mouse transgenes and gene targeting vectors using recombineering technology; mouse ES cell screening (pcr and southern blot) | Renate Lewis |
Viral Vectors | Assist in design/preparation of lentiviral vectors and adeno-associated viral vectors; some shared molecular biology equipment available | Mingjie Li, Joy Snider |
